Parte 1: Epidemiología, fisiopatología y clínica. Seguimiento neumológico de los niños con displasia broncopulmonar al alta de la Unidad de Cuidados. Epidemia de displasia broncopulmonar: incidencia y factores asociados en una cohorte de niños prematuros en Bogotá, Colombia. Juan G. Ruiz-Peláez1,2,3. Displasia Broncopulmonar. ES. eliana silva. Updated 6 September Transcript. Displasia Broncopulmonar Diagnostico general. Nesecidad de mantener.
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Early versus delayed umbilical cord clamping in preterm infants. The scores for each case were determined by adding the scores for each of the four samples The “classic” CLD group received oxygen therapy for the longest period of time Measurement of gene expression in archival paraffin-embedded tissues: Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice.
Camila M, Chaparro P. In the present study, Bcl-2 expression was higher in “classic” CLD than in the group “without” CLD Table 5but this finding has not been statistically significant. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The resulting aggregate called the death-inducing signaling complex DISC performs Caspase 8 proteolytic activation.
The pathophysiology of alveolar hypoplasia, which is present in the “new” CLD, has not been fully elucidated to date. Moller N, Weber T. Prediction of transfusions in extremely low-birthweight infants in the erythropoietin era.
Its expression is increased in cells which are proliferating. On the other hand, the “classic” group had more time for cell differentiation, a process that is characteristic for this phase. Is there a role for erythropoietin in neonatal medicine?
Картинки: Displasia broncopulmonar fisiopatologia
In the group “without” CLD, the length of time of oxygen therapy and the survival time mean 1. Immunohistochemistry staining Tissue microarrays were collected from lung samples from all the cases and analyzed immunohistochemically four samples for each case with 3 mm diameter eachsince this is the most suitable technique to analyze protein expression in this type of material 17 As the alterations in alveolar formation could be very subtle, the samples in groups B and C were analyzed only to confirm the existence of the morphometric criteria of “new” CLD in the group B 17 – 20data are shown in Table 1.
There were no statistically significant differences in PTEN tissue immunoexpression between the “classic” CLD group and the group “without” CLD, compatible with data in literature indicating that “classic” CLD is more associated with inflammatory response than with the apoptosis processe Various studies are currently being carried out to elucidate the pathogenesis of this condition.
Function and regulation of expression of pulmonary surfactant-associated proteins.
X 2 0,; gL 1; p 0, Increased epithelial cell proliferation with chronic lung disease. Proliferating cell nuclear antigen PCNA: Recomendaciones para su tratamiento. J Bras Patol Med Lab.
The medical records were analyzed to collect the data related to the clinical events such as gender, gestational age, ce weight, Apgar score at the first e fifth minute, pregnancy hypertension event, gestational fisiopatologja, chorioamnionitis, longer time with amniotic sac disruption, asphyxia, antibiotic therapy, surfactant therapy, necrotizing enterocolitis, bronchopneumonia, pulmonary hemorrhage, pulmonary hypertension, intracranial hemorrhage, sepsis, corrected age postpartum and time spent on mechanical ventilation and oxygen therapy.
Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia.
PCNA is a nuclear protein which acts as an accessory factor of deoxyribonucleic acid DNA polymerase delta, it is required for DNA replication and repair, and consequently for cell replication lq Aberrant signaling pathways of the lung mesenchyme and their contributions to the pathogenesis of bronchopulmonary dysplasia. Inflammation and bronchopulmonary dysplasia. Preterm rabbits exposed to prolonged hyperoxias as a model for the study fissiopatologia bronchopulmonary dysplasia.
Enhancement and inhibition of apoptosis and cell proliferation play an important role in regulatory mechanisms involved in tissue remodeling 1.
Displasia broncopulmonar fisiopatologia — Поиск по картинкам — [RED]
However, this result might be related to the better long-term survival of the group with “classic” CLD, which allowed more time for cell differentiation and consequently led to increased Bcl-2 expression, indicating higher resistance to apoptosis. The ethics review board of this hospital reviewed and approved the study Register number All alveoli in each medium power field were counted and their perimeters were measured micrometers.
It is known that apoptosis and cell proliferation are implicated in this process and that pulmonary exposure to oxygen and cyclic stretching in mechanical ventilation can trigger changes in the cell-cycle, particularly changes in apoptosis The group “without” CLD was used as the control group for the Dunnett’s test. The staining was interpreted as follows: Red diplasia cell transfusion practices in the neonate.